Myelin相关论文
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social interaction and comm......
Recombinanthumanerythropoietinprotectingneuronand promotingmyelinrepairandfunctionalrecove
Purpose:Theaimofthisstudywastoobserverecombinanthumanerythropoie(rhEPO)onacutespinalcord compressiveinjuryinrats.......
Neurotrophin-4 induces myelin protein zero expression in cultured Schwann cells via TrkB/PI3K/Akt/mT
Myelin formation during peripheral nervous system development, and reformation after injury and in disease, requires mul......
B-cell CLL/lymphoma 11B(Bcl11b),as known as CTIP2,is a C2H2 zinc finger transcriptional factor,functions as a haploinsuf......
Akt(protein kinase B)plays important roles in various biological processes.Recent evidence has shown that mutations on A......
Combination treatment of EGb761 and methylprednisolone reduces tissue damage and improves functional
Methylprednisolone (MP) has been widely used as a standard therapeutic agent for the treatment of spinal cord injury (SC......
Regulatory effects of macrophages on the microenvironment in the damage zone after spinal cord injur
Mouse bone marrow-derived macrophages and fetal brain-derived microglia were isolated and cultured in vitro, then admini......
Stage-dependent regulation of oligodendrocyte differentiation and myelin gene expression by Nkx2.2 t
Nkx2.2 homeodomain transcriptional factor is initially expressed in differentiating oligodendrocyte precursor cells (OPC......
Myelin is essential for the normal function of the vertebrate central nervous system (CNS) and its destruction contribut......
Design,Synthesis and Evaluation of Nile Red Analogs for Myelin Imaging as Potential Near Infrared Im
Myelination is one of the fundamental biological processes in the vertebrate nervous system.Direct detection and quantif......
OBJECTIVE Nicotinamide phos⁃phoribosyltransferase(NAMPT)is the key enzyme for the synthesis of nicotinamide ade⁃nine d......
MYRF:A Mysterious Membrane-bound Transcription Factor Involved in Myelin Development and Human Disea
The myelin regulatory factor gene(MYRF)encodes a protein evolutionarily conserved from invertebrates to vertebrates,repr......
Clemastine rescues behavioral changes and enhances remyelination in the cuprizone mouse model of dem
Increasing evidence suggests that white matter disorders based on myelin sheath impairment may underlie the neuropatholo......
Neuregulin-1 type III is a key regulator in Schwann cell proliferation, committing to a myelinating fate and regulating ......
Contents of myelin-basic protein and S-100 in serum and brain tissue of neonatal rats with intrauter
BACKGROUND: The change of the content of myelin basic protein (MBP) in serum and brain tissue is the biochemical diadyna......
Immunization with inactivated autoreactive T cells(T cell vaccination) selected from individual’s own T cellrepertoire......
The stereoselecfive synthesis of typhoniside,a new cerebrosideisolated from Typhonium giganteum Engl,was accomplished.C......
Since disability in multiple sclerosis(MS) is a product of neurodegeneration and deficient remyelination, the ability to......
Hydroxycitric acid ameliorates inflammation and oxidative stress in mouse models of multiple scleros
Hydroxycitric acid(HCA) is derived primarily from the Garcinia plant and is widely used for its anti-inflammatory effect......
Treatment of multiple sclerosis by transplantation of neural stem cells derived from induced pluripo
Multiple sclerosis(MS) is an autoimmune disease of the central nervous system(CNS), with focal T lymphocytic infiltratio......
Neuroprotective effects of a ketogenic diet in combination with exogenous ketone salts following acu
We have previously shown that induction of ketosis by ketogenic diet (KD) conveyed neuroprotection following spinal cord......
Previous studies have shown that transplantation of human bone marrow mesenchymal stem cells promotes neural functional ......
Salvianolic acid B, an active pharmaceutical compound present inSalvia miltiorrhiza, exerts a neuroprotective effect in ......
Schwann cell development, maturation and regeneration: a focus on classic and emerging intracellular
The development, maturation and regeneration of Schwann cells (SCs), the main glial cells of the periph-eral nervous sys......
[目的]研究大鼠鼻粘膜来源干细胞(REMSCs)分化为施万样细胞与PC12高分化细胞共培养后髓鞘形成及轴突生长情况.[方法]取大鼠鼻甲组......
Genetic factors may be learnt from families with gene mutations that render nerve-injury sus-ceptibility even to ordinar......
Schizophrenia,as a common mental disease,seriously threatens the physical and mental health of human beings.It is charac......
Amyloid precursor protein and growth-associated protein 43 expression in brain white matter and spin
Studies have demonstrated that amyloid precursor protein(APP)expression increases in multiple sclerosis tissues during a......
Carnosine is a dipeptide that scavenges free radicals,inhibits inflammation in the central nervous system,and protects a......
Inflammatory cytokine and iNOS mRNA expression in mononuclear blood cells from patients with multipl
Multiple sclerosis (MS) is an inflammatory demyelination disease of unknown cause. Autoimmunity dh’ected by myelin is ......
Peripheral clonal deletion of MBP-specific T cells by intravenous au-toantigen: rapid reversal of on
Experimental autoimmune encephalomyelitis can be initiated spontaneously and developed progressively in TCR transgenic m......
髓鞘是包绕神经轴突的高度特化的膜性结构,其主要功能是保护轴突、绝缘和维持神经冲动的跳跃式传导。髓鞘膜富含脂质,其脂质构成与......
Wallerian degeneration occurs after peripheral nerve injury and provides a beneficial microenvironment for nerve regener......
目的 探讨化脓性脑膜炎患儿血清和脑脊液(cerebrospinal fluid,CSF)中超敏C反应蛋白(hypersensitivity C reactive protein,hs-CRP......
目的探讨急性一氧化碳中毒(acute carbon monoxide poisoning, ACOP)对大鼠大脑少突胶质前体细胞(oligodendrocyte precursor cell......
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已有的超微结构研究显示,白质中的少突胶质细胞和星形胶质细胞之间存在缝隙连接,但少突胶质细胞之间不存在缝隙连接,虽然体外培养......
本文对体外培养中髓鞘形成与髓鞘再生的研究手段进行综述.探讨各种研究手段的运用历史及优缺点,这些与各实验的研究目的有关.本文......
There is currently no standard pharmacological treatment for spinal cord injury. Here, we suggest that progesterone, a s......
髓鞘形成是一个包括协同性的胞吐、内吞、mRNA转运和细胞骨架的动态变化的复杂过程.尽管髓鞘的异常在溶酶体贮积症中很常见,但对溶......
目的 探讨冰片对大鼠中枢及周围神经髓鞘的影响.方法 SD大鼠根据灌服冰片石蜡油溶液的剂量不同分为低剂量(10 mL/kg)及高剂量(13mL......
目的系统比较髓鞘少突胶质细胞糖蛋白抗体(MOG-IgG)阳性和水通道蛋白4抗体(AQP4-IgG)阳性的视神经脊髓炎谱系疾病(NMOSD)患者的临......
为研究小鼠感染单核细胞增多性李斯特菌(LM)90SB2株后血脑屏障通透性的变化,本实验采用ELISA方法检测小鼠血清中髓鞘碱性蛋白(MBP)......
目的 探讨脑老化时认知功能改变、髓鞘结构和成分变化及其之间关系.方法使用穿梭箱、电镜和免疫组织化学技术,观察了老年大鼠学习......
目的研究大鼠脂肪干细胞(ADSC)来源的施万细胞样细胞的髓鞘形成能力。方法取大鼠脂肪组织分离、培养及鉴定ADSC,使用heregulin、成......
目的：探索一种中枢神经纤维束髓鞘的染色方法。方法：应用丽春红2R-亮绿双重染色法．对正常SD大鼠脊髓组织进行染色。结果：丽春红2R-亮绿......
Objective: To explore the culture conditions of human neural stem cells and to investigate the ultrastructure of neurosp......
目的探讨神经元表达Nogo-A蛋白的情况,对Nogo-A的功能作初步了解.方法采用免疫组织化学方法,观察神经元表达Nogo-A的情况,并设置对......
目的 探讨脑电图联合血清NSE、MBP对病毒性脑炎的诊断及病情评估价值.方法 回顾性分析我院2015年4月至2017年10月我院门诊收治的10......
